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00.250.50.7511.251.51.752+Cadegiani (DB RCT)0.19[0.01-3.90]death0/1142/100RRCITreatmentControlCadegiani (DB RCT)0.08[0.04-0.17]viral+7/17134/66Tau​2 = 0.00; I​2 = 0.0%Early treatment0.08[0.04-0.18]7/28536/16692% improvementCadegiani (DB RCT)0.09[0.05-0.15]death12/294141/296RRCITreatmentControlTau​2 = 0.00; I​2 = 0.0%Late treatment0.09[0.05-0.15]12/294141/29691% improvementAll studies0.08[0.05-0.13]19/579177/46292% improvement3 proxalutamide COVID-19 studiesc19proxalutamide.com 5/8/21Tau​2 = 0.00; I​2 = 0.0%; Z = 10.74 (p < 0.0001)Lower RiskIncreased Risk
3/10
Late Cadegiani et al., Press Conference (Preprint) death, ↓91.4%, p<0.0001 The Proxa-Rescue AndroCoV Trial
RCT 590 hospitalized patients, 294 treated with proxalutamide showing significantly lower mortality and faster recovery.
2/22
Early Cadegiani et al., Cureus, doi:10.7759/cureus.13492 (Peer Reviewed) viral+, ↓92.1%, p<0.0001 Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial
RCT 234 mild-moderate COVID-19 patients with 171 treated with proxalutamide, showing significantly faster viral clearance and recovery.
12/30
Early Cadegiani et al., Research Square, doi:10.21203/rs.3.rs-135303/v1 (Preprint) death, ↓81.1%, p=0.22 Proxalutamide (GT0918) Reduces the Rate of Hospitalization and Death in COVID-19 Male Patients: A Randomized Double-Blinded Placebo-Controlled Trial
RCT 214 male patients in Brazil, 114 treated with proxalutamide, showing significantly lower hospitalization and mechanical ventilation. NCT04446429.
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