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Home   COVID-19 treatment studies for Proxalutamide  COVID-19 treatment studies for Proxalutamide  C19 studies: Proxalutamide  Proxalutamide   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Mortality 63% Improvement Relative Risk Ventilation 90% Hospitalization 86% c19proxalutamide.com Cadegiani et al. Proxalutamide for COVID-19 RCT EARLY Favors proxalutamide Favors control
Cadegiani, 177 patient proxalutamide early treatment RCT: 90% lower ventilation [p=0.07] and 86% lower hospitalization [p=0.0008] https://c19p.org/cadegiani5
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Proxalutamide (GT0918) Reduces the Rate of Hospitalization in mild-to-moderate COVID-19 Female Patients: A Randomized Double-Blinded Placebo-Controlled Two-Arm Parallel Trial
Cadegiani et al., medRxiv, doi:10.1101/2021.07.06.21260086 (Preprint)
10 Jul 2021    Source   PDF   Share   Tweet
RCT 177 women in Brazil, 75 treated with proxalutamide, showing significantly lower hospitalization with treatment.
risk of death, 63.4% lower, RR 0.37, p = 1.00, treatment 0 of 75 (0.0%), control 1 of 102 (1.0%), NNT 102, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of mechanical ventilation, 89.7% lower, RR 0.10, p = 0.07, treatment 0 of 75 (0.0%), control 5 of 102 (4.9%), NNT 20, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of hospitalization, 85.7% lower, RR 0.14, p < 0.001, treatment 2 of 75 (2.7%), control 19 of 102 (18.6%), NNT 6.3.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Cadegiani et al., 7/10/2021, Double Blind Randomized Controlled Trial, Brazil, South America, preprint, 7 authors.
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