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00.250.50.7511.251.51.752+Goren (DB RCT)80%0.20 [0.01-4.13]death0/1342/134Improvement, RR [CI]TreatmentControlCadegiani (DB RCT)92%0.08 [0.04-0.17]viral+7/17134/66Tau​2 = 0.00; I​2 = 0.0%Early treatment92%0.08 [0.04-0.18]7/30536/20092% improvementCadegiani (DB RCT)91%0.09 [0.05-0.15]death12/294141/296Improvement, RR [CI]TreatmentControlTau​2 = 0.00; I​2 = 0.0%Late treatment91%0.09 [0.05-0.15]12/294141/29691% improvementAll studies91%0.09 [0.05-0.13]19/599177/49691% improvement3 proxalutamide COVID-19 studiesc19proxalutamide.com 6/21/21Tau​2 = 0.00; I​2 = 0.0%; Z = 10.74 (p < 0.0001)Lower RiskIncreased Risk
3/10
Late Cadegiani et al., Press Conference (Preprint) death, ↓91.4%, p<0.0001 The Proxa-Rescue AndroCoV Trial
Details   RCT 590 hospitalized patients, 294 treated with proxalutamide showing significantly lower mortality and faster recovery.
2/22
Early Cadegiani et al., Cureus, doi:10.7759/cureus.13492 (Peer Reviewed) viral+, ↓92.1%, p<0.0001 Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial
Details   RCT 234 mild-moderate COVID-19 patients with 171 treated with proxalutamide, showing significantly faster viral clearance and recovery.
12/30
Early Goren et al., Frontiers in Medicine, doi:10.3389/fmed.2021.668698 (preprint 12/30/2020) (Peer Reviewed) death, ↓80.0%, p=0.50 Proxalutamide (GT0918) Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial
Details   RCT 268 male patients in Brazil, 134 treated with proxalutamide, showing significantly lower hospitalization and mechanical ventilation. NCT04446429.
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